Two new dimeric and trimeric sesquiterpene lactones (1–2), and nine known sesquiterpene lactones (3–11) were isolated from the EtOAc phase of the ethanolic extract of Ainsliaea yunnanensis. Their structures were identified by NMR, IR and HR-ESIMS spectroscopic methods, and compound 1 was confirmed by single crystal X-ray diffraction experiment. All the compounds were tested for their cytotoxic, anti-microbial and anti-inflammatory activities. Compounds 1, 2, 3, 5, 7, 9 and 11 showed very significant selective cytotoxic...

Supplemental material, sj-docx-1-hol-10.1177_09596836221131694 for Hydro-climatic aspects of prehistoric human dynamics in the drylands of the Asian interior by Kangkang Li, Xiaoguang Qin, Bing Xu, Zhiqiang Yin, Yong Wu, Guijin Mu, Dong Wei, Xiaohong Tian, Huiqiu Shao, Chunxue Wang, Hongjuan Jia, Wen Li, Haoze Song, Jiaqi Liu and Yingxin Jiao in The Holocene

Two new dimeric and trimeric sesquiterpene lactones (1–2), and nine known sesquiterpene lactones (3–11) were isolated from the EtOAc phase of the ethanolic extract of Ainsliaea yunnanensis. Their structures were identified by NMR, IR and HR-ESIMS spectroscopic methods, and compound 1 was confirmed by single crystal X-ray diffraction experiment. All the compounds were tested for their cytotoxic, anti-microbial and anti-inflammatory activities. Compounds 1, 2, 3, 5, 7, 9 and 11 showed very significant selective cytotoxic...

Additional file 1. Additional figures and legends.

Additional file 1. Additional figures and legends.

Additional file 1.

To explore the distribution law of traditional Chinese medicine (TCM) syndrome types in patients with psoriasis vulgaris complicated by metabolic disorders based on the same pathogenic factors as blood-heat and blood-stasis in the pathogenesis of psoriasis and metabolic disorders and to further analyze the correlation between adiponectin and the distribution law. From January 1, 2018, to December 31, 2019, patients diagnosed with psoriasis in the inpatient or outpatient department of Dermatology Ward of Shanghai Yueyang...

Additional file 2.

A novel fluorescence and colorimetric dual probe based upon the inner filter effect (IFE) is reported to selectively and sensitively determine alkaline phosphatase (ALP). First, up-conversion nanoparticles (UCNPs) were prepared via a facile hydrothermal method and characterized by transmission electron microscopy (TEM), X-ray diffractometry (XRD), Fourier transform infrared spectroscopy (FT-IR), and zeta potential. Under near infrared (NIR) excitation at 980 nm, the prepared nanoparticles emit green light at 541 nm. The absorption band of p-phenylenediamine...

Additional file 1: Figure S1. The histogram of the number of survival neurons in hippocampal CA1 and CA3 regions of APP/PS1 mice. KXS-H: 10g/kg/day. The experiment data are expressed as means ± SEM. n = 3 in each group. ###P < 0.001 vs. Ctrl group; ∗P < 0.05 vs. APP/PS1 group. Figure S2. The histogram of immunofluorescent about SIRT3 and NLRP3 in the hippocampus of APP/PS1 mice. n = 3 in each group. ###P <...

Additional file 1: Figure S1. The histogram of the number of survival neurons in hippocampal CA1 and CA3 regions of APP/PS1 mice. KXS-H: 10g/kg/day. The experiment data are expressed as means ± SEM. n = 3 in each group. ###P < 0.001 vs. Ctrl group; ∗P < 0.05 vs. APP/PS1 group. Figure S2. The histogram of immunofluorescent about SIRT3 and NLRP3 in the hippocampus of APP/PS1 mice. n = 3 in each group. ###P <...

Additional file 1.

Additional file 2.

To explore the distribution law of traditional Chinese medicine (TCM) syndrome types in patients with psoriasis vulgaris complicated by metabolic disorders based on the same pathogenic factors as blood-heat and blood-stasis in the pathogenesis of psoriasis and metabolic disorders and to further analyze the correlation between adiponectin and the distribution law. From 1 January 2018 to 31 December 2019, patients diagnosed with psoriasis in the inpatient or outpatient department of Dermatology Ward of Shanghai Yueyang...

A novel fluorescence and colorimetric dual probe based upon the inner filter effect (IFE) is reported to selectively and sensitively determine alkaline phosphatase (ALP). First, up-conversion nanoparticles (UCNPs) were prepared via a facile hydrothermal method and characterized by transmission electron microscopy (TEM), X-ray diffractometry (XRD), Fourier transform infrared spectroscopy (FT-IR), and zeta potential. Under near infrared (NIR) excitation at 980 nm, the prepared nanoparticles emit green light at 541 nm. The absorption band of p-phenylenediamine...

Supplemental material, sj-docx-1-hol-10.1177_09596836221131694 for Hydro-climatic aspects of prehistoric human dynamics in the drylands of the Asian interior by Kangkang Li, Xiaoguang Qin, Bing Xu, Zhiqiang Yin, Yong Wu, Guijin Mu, Dong Wei, Xiaohong Tian, Huiqiu Shao, Chunxue Wang, Hongjuan Jia, Wen Li, Haoze Song, Jiaqi Liu and Yingxin Jiao in The Holocene

To explore the distribution law of traditional Chinese medicine (TCM) syndrome types in patients with psoriasis vulgaris complicated by metabolic disorders based on the same pathogenic factors as blood-heat and blood-stasis in the pathogenesis of psoriasis and metabolic disorders and to further analyze the correlation between adiponectin and the distribution law. From 1 January 2018 to 31 December 2019, patients diagnosed with psoriasis in the inpatient or outpatient department of Dermatology Ward of Shanghai Yueyang...