Additional file1: Supplementary Table 1. Clinical, instrumental, histological and molecular features of CHKB-mutated MCMD patients reported so far (y: years; m: months; d: days; NA: not assessed; DCM: dilated cardiomyopathy; LVFS: left ventricular systolic function; PDA: Patent ductus arteriosus).

Additional file 2. Informed consent.

Supplemental material, sj-pdf-1-jcb-10.1177_0271678X231159958 for Harmonization of sensorimotor deficit assessment in a registered multicentre pre-clinical randomized controlled trial using two models of ischemic stroke by Alessia Valente, Jacopo Mariani, Serena Seminara, Mauro Tettamanti, Giuseppe Pignataro, Carlo Perego, Luigi Sironi, Felicita Pedata, Diana Amantea, Marco Bacigaluppi, Antonio Vinciguerra, Susanna Diamanti, Martina Viganò, Francesco Santangelo, Chiara Paola Zoia, Virginia Rodriguez-Menendez, Laura Castiglioni, Joanna Rzemieniec, Ilaria Dettori, Irene Bulli, Elisabetta Coppi, Chiara Di Santo, Ornella Cuomo, Giorgia Serena Gullotta,...

Supplemental material, sj-pdf-2-jcb-10.1177_0271678X231159958 for Harmonization of sensorimotor deficit assessment in a registered multicentre pre-clinical randomized controlled trial using two models of ischemic stroke by Alessia Valente, Jacopo Mariani, Serena Seminara, Mauro Tettamanti, Giuseppe Pignataro, Carlo Perego, Luigi Sironi, Felicita Pedata, Diana Amantea, Marco Bacigaluppi, Antonio Vinciguerra, Susanna Diamanti, Martina Viganò, Francesco Santangelo, Chiara Paola Zoia, Virginia Rodriguez-Menendez, Laura Castiglioni, Joanna Rzemieniec, Ilaria Dettori, Irene Bulli, Elisabetta Coppi, Chiara Di Santo, Ornella Cuomo, Giorgia Serena Gullotta,...

hRPE65 is a fundamental enzyme of the retinoid visual cycle, and many missense mutations affecting its expression or function are associated with a wide range of diseases. Many hRPE65 missense mutations lack a clear pathogenicity classification or are labelled as VUS. In this context, we recently developed a protocol based on µs-long molecular dynamics simulations to study the potential pathogenic effect of hRPE65 missense mutations. In the present work, the structure-based protocol was integrated with...

To investigate the responsiveness and minimal clinically important difference (MCID) of the Functional Independence Measure (FIM) from a clinician’s perspective in hip-fractured elderly undergoing inpatient rehabilitation. Data of 701 hip-fractured elderly admitted to our rehabilitation institute were retrospectively collected. Ten a priori hypotheses were formulated. The effect size of the FIM scores after treatment were large (total = 1.38, motor = 1.78). Moderate correlations were found between the change total score of FIM and Barthel...

hRPE65 is a fundamental enzyme of the retinoid visual cycle, and many missense mutations affecting its expression or function are associated with a wide range of diseases. Many hRPE65 missense mutations lack a clear pathogenicity classification or are labelled as VUS. In this context, we recently developed a protocol based on µs-long molecular dynamics simulations to study the potential pathogenic effect of hRPE65 missense mutations. In the present work, the structure-based protocol was integrated with...

This meta-analysis aims to assess the effectiveness of the current Sars-Cov2 vaccine regimens against Omicron infection. A secondary endpoint aims to investigate the waning effectiveness of primary vaccination against symptomatic infection and related hospitalization. The systematic review started on 1 December 2021 and was concluded on 1 March 2022. Random-effects frequentist meta-analyses and multiple meta-regressions were performed. In total, 15 studies are included in the quantitative synthesis. According to the meta-analysis results, the overall risk...

Additional file 1: Appendix I.

Supplemental material, sj-pdf-1-tmj-10.1177_03008916231154765 for Upper-neck irradiation versus standard whole-neck irradiation in nasopharyngeal carcinoma: A systematic review and meta-analysis by Francesca De Felice, Claudia Marchetti, Maria Serpone, AnnaMaria Camarda, Barbara Vischioni, Rossana Ingargiola, Daniela Musio and Ester Orlandi in Tumori Journal

Additional file 2. Informed consent.

Additional file 1. SPIRIT Checklist.

Supplemental material, sj-docx-1-tag-10.1177_17562848221136328 for Phylogenetic analysis of Prevotella copri from fecal and mucosal microbiota of IBS and IBD patients by Alessandra Lo Presti, Federica Del Chierico, Annamaria Altomare, Francesca Zorzi, Giovanni Monteleone, Lorenza Putignani, Silvia Angeletti, Michele Cicala, Michele Pier Luca Guarino and Massimo Ciccozzi in Therapeutic Advances in Gastroenterology

Supplemental material, sj-docx-1-tag-10.1177_17562848221136328 for Phylogenetic analysis of Prevotella copri from fecal and mucosal microbiota of IBS and IBD patients by Alessandra Lo Presti, Federica Del Chierico, Annamaria Altomare, Francesca Zorzi, Giovanni Monteleone, Lorenza Putignani, Silvia Angeletti, Michele Cicala, Michele Pier Luca Guarino and Massimo Ciccozzi in Therapeutic Advances in Gastroenterology

This meta-analysis aims to assess the effectiveness of the current Sars-Cov2 vaccine regimens against Omicron infection. A secondary endpoint aims to investigate the waning effectiveness of primary vaccination against symptomatic infection and related hospitalization. The systematic review started on 1 December 2021 and was concluded on 1 March 2022. Random-effects frequentist meta-analyses and multiple meta-regressions were performed. In total, 15 studies are included in the quantitative synthesis. According to the meta-analysis results, the overall risk...

Additional file 1. Table S1. List of the SNPs analysed. Table S2. Other uncommon Adverse Events–maximum grade. Table S3. QOL scores – change from baseline to third cycle. Table S4. QOL scores – change from baseline to end of treatment. Table S5. Frequency of variants of all the 15 SNPs and the prevalence of each polymorphism was compared with the expected prevalence in Europe. Table S6. Number of eribulin cycles based on previous neurotoxicity.

Supplementary Material 1: Table 1S: Baseline characteristics of patients hospitalized with ST-elevation myocardial infarction (STEMI) according to diabetes mellitus status and its duration, from 2010 to 2019. Table 2S: In hospital complications and procedures in patients hospitalized with ST-elevation myocardial infarction (STEMI) according to diabetes mellitus status and its duration, from 2010 to 2019. Table 3S: Baseline characteristics of patients hospitalized with non-ST-elevation myocardial infarction (NSTEMI) according to diabetes mellitus status and its duration, from...

Supplemental material, sj-docx-1-tam-10.1177_17588359221138657 for Development of a nomogram for predicting pathological complete response in luminal breast cancer patients following neoadjuvant chemotherapy by Giovanna Garufi, Luisa Carbognin, Isabella Sperduti, Federica Miglietta, Maria Vittoria Dieci, Roberta Mazzeo, Armando Orlandi, Lorenzo Gerratana, Antonella Palazzo, Alessandra Fabi, Ida Paris, Antonio Franco, Gianluca Franceschini, Elena Fiorio, Sara Pilotto, Valentina Guarneri, Fabio Puglisi, Pierfranco Conte, Michele Milella, Giovanni Scambia, Giampaolo Tortora and Emilio Bria in Therapeutic Advances in Medical Oncology

Supplemental material, sj-docx-1-tam-10.1177_17588359221138657 for Development of a nomogram for predicting pathological complete response in luminal breast cancer patients following neoadjuvant chemotherapy by Giovanna Garufi, Luisa Carbognin, Isabella Sperduti, Federica Miglietta, Maria Vittoria Dieci, Roberta Mazzeo, Armando Orlandi, Lorenzo Gerratana, Antonella Palazzo, Alessandra Fabi, Ida Paris, Antonio Franco, Gianluca Franceschini, Elena Fiorio, Sara Pilotto, Valentina Guarneri, Fabio Puglisi, Pierfranco Conte, Michele Milella, Giovanni Scambia, Giampaolo Tortora and Emilio Bria in Therapeutic Advances in Medical Oncology

Supplemental material, sj-docx-2-tam-10.1177_17588359221138657 for Development of a nomogram for predicting pathological complete response in luminal breast cancer patients following neoadjuvant chemotherapy by Giovanna Garufi, Luisa Carbognin, Isabella Sperduti, Federica Miglietta, Maria Vittoria Dieci, Roberta Mazzeo, Armando Orlandi, Lorenzo Gerratana, Antonella Palazzo, Alessandra Fabi, Ida Paris, Antonio Franco, Gianluca Franceschini, Elena Fiorio, Sara Pilotto, Valentina Guarneri, Fabio Puglisi, Pierfranco Conte, Michele Milella, Giovanni Scambia, Giampaolo Tortora and Emilio Bria in Therapeutic Advances in Medical Oncology

To investigate the responsiveness and minimal clinically important difference (MCID) of the Functional Independence Measure (FIM) from a clinician’s perspective in hip-fractured elderly undergoing inpatient rehabilitation. Data of 701 hip-fractured elderly admitted to our rehabilitation institute were retrospectively collected. Ten a priori hypotheses were formulated. The effect size of the FIM scores after treatment were large (total = 1.38, motor = 1.78). Moderate correlations were found between the change total score of FIM and Barthel...

Additional file 1: Appendix I.

Additional file 1: Table S1. Predictors of DMC in the overall population by univariate and multivariate logistic regression analysis. Table S2. Clinical, echocardiographic and angiographic features in the overall OCT population according to the presence or absence of DMC. Table S3. Sensitivity analysis of OCT characteristics of coronary plaques in the culprit vessel according to the presence or absence of diabetic microvascular complications excluding patients with diabetic neuropathy. Table S4. Predictors of large calcifications in...

Additional file 1: Table S1. Predictors of DMC in the overall population by univariate and multivariate logistic regression analysis. Table S2. Clinical, echocardiographic and angiographic features in the overall OCT population according to the presence or absence of DMC. Table S3. Sensitivity analysis of OCT characteristics of coronary plaques in the culprit vessel according to the presence or absence of diabetic microvascular complications excluding patients with diabetic neuropathy. Table S4. Predictors of large calcifications in...

Additional file1: Supplementary Table 1. Clinical, instrumental, histological and molecular features of CHKB-mutated MCMD patients reported so far (y: years; m: months; d: days; NA: not assessed; DCM: dilated cardiomyopathy; LVFS: left ventricular systolic function; PDA: Patent ductus arteriosus).