1,665 Works

Additional file 1 of IgG response to spike protein of SARS-CoV-2 in healthy individuals and potential of intravenous IgG as treatment for COVID-19

Gang Wang, Zebao He, Fengtian Wu, Zhengming Ge, Jiansheng Zhu & Zhi Chen
Additional file1. Table S1. The ID ofeach referenced coronavirus. Fig. S1. Envelopprotein alignment. Fig. S2. Membrane protein alignment. Fig. S3 Spikprotein alignment

Additional file 2 of Genetic analysis of 55 cases with fetal skeletal dysplasia

Ying Bai, Yue Sun, Ning Liu, Li Wang, Zhihui Jiao, Yaqin Hou, Huikun Duan, Qianqian Li, Xiaofan Zhu, Jingjing Meng & Xiangdong Kong
Additional file 2. Images of US examination of some fetuses in this study.

Additional file 1 of Sex differences in clinical cognitive impairment with Lewy bodies: a Chinese multicenter study

Jinghuan Gan, Zhichao Chen, Zhihong Shi, Xudong Li, Shuai Liu, Yiming Liu, Hongcan Zhu, Lu Shen, Guili Zhang, Yong You, Qihao Guo, Nan Zhang, Yang Lv, Baozhi Gang, Junliang Yuan & Yong Ji
Additional file 1: eAppendix 1. Information of participating clinics. eAppendix 2. Details of APOE genotyping. eAppendix 3. MRI parameters and review. Table S1. Sex-specific characteristics of the four groups

Additional file 1 of The effectiveness of case management for cancer patients: an umbrella review

Nina Wang, Jia Chen, Wenjun Chen, Zhengkun Shi, Huaping Yang, Peng Liu, Xiao Wei, Xiangling Dong, Chen Wang, Ling Mao & Xianhong Li
Additional file 1.

Melittin induces ferroptosis and ER stress-CHOP-mediated apoptosis in A549 cells

Xuan Li, Sen Zhu, Zheng Li, Yu-Qi Meng, Su-Jie Huang, Qi-Yao Yu & Bin Li
Melittin is a natural polypeptide present in bee venom, with significant anti-tumor activity. Melittin has been reported to induce cell death in lung carcinoma cell line A549 cells, suggesting an excellent potential for treating lung cancer. However, the core mechanism underlying melittin-induced cell death in A549 cells remains unclear. This work reports that melittin induces reactive oxygen species (ROS) burst, upregulates intracellular Fe2+ levels, disrupts the glutathione-glutathione peroxidase 4 antioxidant system, and increases lipid peroxide...

Additional file 1 of CCHCR1-astrin interaction promotes centriole duplication through recruitment of CEP72

Zhenguang Ying, Kaifang Wang, Junfeng Wu, Mingyu Wang, Jing Yang, Xia Wang, Guowei Zhou, Haibin Chen, Hongwu Xu, Stephen Cho Wing Sze, Feng Gao, Chunman Li & Ou Sha
Additional file 1: Fig. S1. Repeated verification of the interaction between HCR and astrin. (A) Astrin Co-IP HCR and CEP72 and HCR Co-IP astrin and CEP72. HeLa cell lysates were immunoprecipitated with astrin, HCR, or control rabbit IgG antibodies and analyzed by western blotting with anti-astrin, anti-HCR antibodies. Anti-GM130 and anti-beta actin antibodies were used as negative control. The blotting of astrin, HCR and GM130 antibodies were incubated on the same membrane by repeatedly washing...

Additional file 3 of CCHCR1-astrin interaction promotes centriole duplication through recruitment of CEP72

Zhenguang Ying, Kaifang Wang, Junfeng Wu, Mingyu Wang, Jing Yang, Xia Wang, Guowei Zhou, Haibin Chen, Hongwu Xu, Stephen Cho Wing Sze, Feng Gao, Chunman Li & Ou Sha
Additional file 3: Fig. S3. Apoptosis or cycle changes in astrin-KO cells and identification of astrin-KO cell line. (A) Parental, astrin-KO and HCR-KO HeLa cells were analyzed with astrin, HCR, cyclin B1 and Cleaved PARP antibodies. HeLa cells treated with DMSO, Paclitaxel, Bafilomycin and MG132 were analyzed with Cleaved PARP and HCR antibodies. (B) Parental and astrin-KO HeLa cells were immunoblotted with an astrin antibody.

Additional file 5 of CCHCR1-astrin interaction promotes centriole duplication through recruitment of CEP72

Zhenguang Ying, Kaifang Wang, Junfeng Wu, Mingyu Wang, Jing Yang, Xia Wang, Guowei Zhou, Haibin Chen, Hongwu Xu, Stephen Cho Wing Sze, Feng Gao, Chunman Li & Ou Sha
Additional file 5: Fig. S8. Co-localization of HCR with centrin1 and PCM1. HeLa cells transfected with HCR-GFP were co-stain with centrin1 (red) and gamma-tubulin (cyan) and DAPI (blue) or PCM1 (red) and gamma-tubulin (cyan) and DAPI (blue); scale bars, 10 μm. Fig. S9. HCR interacts with CEP131. HeLa cell lysates were immunoprecipitated with antibodies specific for HCR, astrin, or negative control rabbit IgG. The precipitates were analyzed by immunoblotting with antibodies against HCR and CEP131....

Additional file 8 of CCHCR1-astrin interaction promotes centriole duplication through recruitment of CEP72

Zhenguang Ying, Kaifang Wang, Junfeng Wu, Mingyu Wang, Jing Yang, Xia Wang, Guowei Zhou, Haibin Chen, Hongwu Xu, Stephen Cho Wing Sze, Feng Gao, Chunman Li & Ou Sha
Additional file 8. Verification reports of HCR-KO cell line.

Additional file 9 of CCHCR1-astrin interaction promotes centriole duplication through recruitment of CEP72

Zhenguang Ying, Kaifang Wang, Junfeng Wu, Mingyu Wang, Jing Yang, Xia Wang, Guowei Zhou, Haibin Chen, Hongwu Xu, Stephen Cho Wing Sze, Feng Gao, Chunman Li & Ou Sha
Additional file 9. Verification reports of astrin-KO cell line.

Additional file 5 of Genome-wide identification and characterization of lncRNAs in sunflower endosperm

Shuai Yu, Zhichao Zhang, Jing Li, Yanbin Zhu, Yanzhe Yin, Xiaoyu Zhang, Yuxin Dai, Ao Zhang, Cong Li, Yanshu Zhu, Jinjuan Fan, Yanye Ruan & Xiaomei Dong
Additional file 5: Fig. S2. Expression levels of lncRNAs and PCgenes in sunflower endosperm.

Additional file 1 of Dynamic prediction of life-threatening events for patients in intensive care unit

Jiang Hu, Xiao-hui Kang, Fang-fang Xu, Ke-zhi Huang, Bin Du & Li Weng
Additional file 1. The AUCs of predictors after excluding the cases of electric defibrillation.

Additional file 1 of Dynamic prediction of life-threatening events for patients in intensive care unit

Jiang Hu, Xiao-hui Kang, Fang-fang Xu, Ke-zhi Huang, Bin Du & Li Weng
Additional file 1. The AUCs of predictors after excluding the cases of electric defibrillation.

Additional file 2 of Dynamic prediction of life-threatening events for patients in intensive care unit

Jiang Hu, Xiao-hui Kang, Fang-fang Xu, Ke-zhi Huang, Bin Du & Li Weng
Additional file 2. The AUCs of predictors for randomly selecting one positive sample and one negative sample from each patient.

Additional file 1 of Identification of risk factors for incident cervical insufficiency in nulliparous and parous women: a population-based case-control study

Lili Meng, Sara Öberg, Anna Sandström, Chen Wang & Marie Reilly
Additional file 1: Table S1. ICD codes used to define medical diagnoses and surgical procedures.

Additional file 1 of Risk factors of in-home unintentional injuries among 0-6-year-old children in Changsha city of China: a cross-sectional survey based on Bronfenbrenner’s ecological system theory

Yihan Ma, Juan Song, Ming Hu, Rusi Yang & Panzi Yang
Additional file 1: Supplementary Table 1. Standardized factor loading for latent variables in the measurement model. Supplementary Table 2. AVE, correlations, and squared correlations of the latent variables. Supplementary Table 3. Fit values of each latent variable in the measurement model. Supplementary Table 4. The indirect, direct, and total effects of parental supervision and home environmental risks on IUIs.

Additional file 1 of CRISPR/Cas9-targeted mutagenesis of a representative member of a novel PR10/Bet v1-like protein subfamily significantly reduces rice plant height and defense against Meloidogyne graminicola

Zhiwen Li, Qiuling Huang, Borong Lin, Bin Guo, Jing Wang, Chunhui Huang, Jinling Liao & Kan Zhuo
Additional file 1: Figure S1. Pairwise sequence identify matrix for plant PR10/Bet v1-like protein sequences. Red and green boxes indicate high and low pairwise identity. Figure S2. Architecture of conserved regions in plant PR10/Bet v1-like proteins.

The ROS/NF-κB/HK2 axis is involved in the arsenic-induced Warburg effect in human L-02 hepatocytes

Fanshuo Yin, Ying Zhang, Xin Zhang, Meichen Zhang, Zaihong Zhang, Yunyi Yin, Haili Xu, Yanmei Yang & Yanhui Gao
Arsenic has been identified as a carcinogen, although the molecular mechanism underlying itscarcinogenesis has not been fully elucidated. To date, only a few studies have attempted to confirm a direct link between oxidative stress and the Warburg effect . This study demonstrated that 0.2 μmol/L As3+ induced the Warburg effect to contribute to abnormal proliferation of L-02 cells, that was mediated by upregulation of hexokinase 2 (HK2), a key enzyme in glycolysis. Further study indicated...

Additional file 1 of Lymphocyte to C-reactive protein ratio could better predict the prognosis of patients with stage IV cancer

He-Yang Zhang, Hai-Lun Xie, Guo-Tian Ruan, Qi Zhang, Yi-Zhong Ge, Xiao-Yue Liu, Meng Tang, Meng-Meng Song, Shi-Qi Lin, Ming Yang, Xiao-Wei Zhang, Hong-Xia Xu, Chun-Hua Song & Han-Ping Shi
Additional file 1.

Additional file 1 of Botulinum toxin treatment for bielschowsky acquired comitant esotropia in adults

Likun Ai, Xiaoli Chen, Ruilin Guo, Jing Li, Jinghui Wang, Yi Feng, Yiqin Guo & Jianan Wang
Supplementary Material 1

Additional file 1 of Genetic engineering and raising temperature enhance recombinant protein production with the cdna1 promoter in Trichoderma reesei

Shanshan Jiang, Yue Wang, Qin Liu, Qinqin Zhao, Liwei Gao, Xin Song, Xuezhi Li, Yinbo Qu & Guodong Liu
Additional file 1: Table S1. Primers used for strain construction and verification in this study. Table S2. Primers used for qPCR in this study. Table S3. Copy numbers of poman5A gene in the constructed strains measured by qPCR. Figure S1. Map of plasmid pM5p.

Additional file 1 of Ambient air pollution associated with incidence and dynamic progression of type 2 diabetes: a trajectory analysis of a population-based cohort

Yinglin Wu, Shiyu Zhang, Samantha E. Qian, Miao Cai, Haitao Li, Chongjian Wang, Hongtao Zou, Lan Chen, Michael G. Vaughn, Stephen Edward McMillin & Hualiang Lin
Additional file 1: Details of outcomes. Table S1. The UDI, definition and measurements of covariates. Table S2. Characteristics of the participants included or excluded in the study. Table S3. Distributions of the annual average exposures among 398,993 participants. Table S4. Associations between air pollution and risk of cause-specific mortality. Table S5. Results of 2-pollutant models. Table S6. Results of sensitivity analyses in the model including traffic noise (n = 393,515). Table S7. Results of sensitivity...

sj-docx-1-cre-10.1177_02692155221136046 - Supplemental material for Effect of pelvic floor muscle training on urinary incontinence after radical prostatectomy: An umbrella review of meta-analysis and systematic review

Jia-ming Yang, Hua Ye, Yi Long, Qiang Zhu, Hui Huang, Hui-yong Xie, Yun Luo, Yan-biao Zhong, Jing Chen & Mao-yuan Wang
Supplemental material, sj-docx-1-cre-10.1177_02692155221136046 for Effect of pelvic floor muscle training on urinary incontinence after radical prostatectomy: An umbrella review of meta-analysis and systematic review by Jia-ming Yang, Hua Ye, Yi Long, Qiang Zhu, Hui Huang, Hui-yong Xie, Yun Luo, Yan-biao Zhong, Jing Chen and Mao-yuan Wang in Clinical Rehabilitation

Additional file 1 of Gender-specific relationship between frequency of food-away-from-home with serum lipid levels and dyslipidemia in chinese rural adults

Yuyang Wang, Xiaotian Liu, Xiaokang Dong, Beibei Liu, Ning Kang, Wenqian Huo, Zhenxing Mao, Jian Hou & Chongjian Wang
Supplementary Material 1

Additional file 1 of Loss of miR-637 promotes cancer cell stemness via WASH/IL-8 pathway and serves as a novel prognostic marker in esophageal squamous cell carcinoma

Mengxing Guo, Jingyao Lian, Yaqing Liu, Bo Dong, Qianyi He, Qitai Zhao, Hongyan Zhang, Yu Qi, Yi Zhang & Lan Huang
Additional file 1: Supplementary Table S1. Primer Sequences for qRT-PCR assays.

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