17 Works
Additional file 2 of Accrual of organ damage in Behçet’s syndrome: trajectory, associated factors, and impact on patients’ quality of life over a 2-year prospective follow-up study
Alberto Floris, Matteo Piga, Riccardo Laconi, Gerard Espinosa, Giuseppe Lopalco, Luisa Serpa Pinto, Nikolaos Kougkas, Jurgen Sota, Andrea Lo Monaco, Marcello Govoni, Luca Cantarini, George Bertsias, João Correia, Florenzo Iannone, Ricard Cervera, Carlos Vasconcelos, Alessandro Mathieu & Alberto Cauli
Additional file 2: Supplementary Table 1. Baseline features of the extension BODI cohort recruited for the analysis of the association between damage accrual and Heath related quality of life (n=147).
Additional file 1 of Safety, efficacy, and pharmacokinetics of gremubamab (MEDI3902), an anti-Pseudomonas aeruginosa bispecific human monoclonal antibody, in P. aeruginosa-colonised, mechanically ventilated intensive care unit patients: a randomised controlled trial
Jean Chastre, Bruno François, Marc Bourgeois, Apostolos Komnos, Ricard Ferrer, Galia Rahav, Nicolas De Schryver, Alain Lepape, Iftihar Koksal, Charles-Edouard Luyt, Miguel Sánchez-García, Antoni Torres, Philippe Eggimann, Despoina Koulenti, Thomas L. Holland, Omar Ali, Kathryn Shoemaker, Pin Ren, Julien Sauser, Alexey Ruzin, David E. Tabor, Ahmad Akhgar, Yuling Wu, Yu Jiang, Antonio DiGiandomenico … & Hasan S. Jafri
Additional file 1: Supplementary Methods, Results, Tables and Figures.
Additional file 9 of scTAM-seq enables targeted high-confidence analysis of DNA methylation in single cells
Agostina Bianchi, Michael Scherer, Roser Zaurin, Kimberly Quililan, Lars Velten & Renée Beekman
Additional file 9. Review history.
Additional file 1 of Clinical research diagnostic criteria for bipolar illness (CRDC-BP): rationale and validity
S. Nassir Ghaemi, Jules Angst, Paul A. Vohringer, Eric A. Youngstrom, James Phelps, Philip B. Mitchell, Roger S. McIntyre, Michael Bauer, Eduard Vieta & Samuel Gershon
Additional file 1. Online Supplementary Appendix: Clinical Research Diagnostic Criteria for BipolarDisorder.
Additional file 1 of Clinical research diagnostic criteria for bipolar illness (CRDC-BP): rationale and validity
S. Nassir Ghaemi, Jules Angst, Paul A. Vohringer, Eric A. Youngstrom, James Phelps, Philip B. Mitchell, Roger S. McIntyre, Michael Bauer, Eduard Vieta & Samuel Gershon
Additional file 1. Online Supplementary Appendix: Clinical Research Diagnostic Criteria for BipolarDisorder.
Additional file 1 of Stress response during early sedation with dexmedetomidine compared with usual-care in ventilated critically ill patients
John P. R. Moore, Yahya Shehabi, Michael C. Reade, Michael Bailey, John F. Fraser, Lauren Murray, Christopher Anstey & Mervyn Singer
Additional file 1. Appendix 1. Supplementary figures and tables.
Additional file 9 of scTAM-seq enables targeted high-confidence analysis of DNA methylation in single cells
Agostina Bianchi, Michael Scherer, Roser Zaurin, Kimberly Quililan, Lars Velten & Renée Beekman
Additional file 9. Review history.
Additional file 1 of Accrual of organ damage in Behçet’s syndrome: trajectory, associated factors, and impact on patients’ quality of life over a 2-year prospective follow-up study
Alberto Floris, Matteo Piga, Riccardo Laconi, Gerard Espinosa, Giuseppe Lopalco, Luisa Serpa Pinto, Nikolaos Kougkas, Jurgen Sota, Andrea Lo Monaco, Marcello Govoni, Luca Cantarini, George Bertsias, João Correia, Florenzo Iannone, Ricard Cervera, Carlos Vasconcelos, Alessandro Mathieu & Alberto Cauli
Additional file 1: Supplementary Figure 1. Flow chart representing the patients’ recruiting process from the BODI validation cohort.
Additional file 1 of Accrual of organ damage in Behçet’s syndrome: trajectory, associated factors, and impact on patients’ quality of life over a 2-year prospective follow-up study
Alberto Floris, Matteo Piga, Riccardo Laconi, Gerard Espinosa, Giuseppe Lopalco, Luisa Serpa Pinto, Nikolaos Kougkas, Jurgen Sota, Andrea Lo Monaco, Marcello Govoni, Luca Cantarini, George Bertsias, João Correia, Florenzo Iannone, Ricard Cervera, Carlos Vasconcelos, Alessandro Mathieu & Alberto Cauli
Additional file 1: Supplementary Figure 1. Flow chart representing the patients’ recruiting process from the BODI validation cohort.
Autophagy-mediated NCOR1 degradation is required for brown fat maturation and thermogenesis
Alba Sabaté-Pérez, Montserrat Romero, Paula Sànchez-Fernàndez-de-Landa, Stefania Carobbio, Michail Mouratidis, David Sala, Pablo Engel, Josep A Villena, Sam Virtue, Antonio Vidal-Puig, Manuel Palacín, Xavier Testar & Antonio Zorzano
Brown adipose tissue (BAT) thermogenesis affects energy balance, and thereby it has the potential to induce weight loss and to prevent obesity. Here, we document a macroautophagic/autophagic-dependent mechanism of peroxisome proliferator-activated receptor gamma (PPARG) activity regulation that induces brown adipose differentiation and thermogenesis and that is mediated by TP53INP2. Disruption of TP53INP2-dependent autophagy reduced brown adipogenesis in cultured cells. In vivo specific-tp53inp2 ablation in brown precursor cells or in adult mice decreased the expression of...
Additional file 1 of Stress response during early sedation with dexmedetomidine compared with usual-care in ventilated critically ill patients
John P. R. Moore, Yahya Shehabi, Michael C. Reade, Michael Bailey, John F. Fraser, Lauren Murray, Christopher Anstey & Mervyn Singer
Additional file 1. Appendix 1. Supplementary figures and tables.
Additional file 1 of scTAM-seq enables targeted high-confidence analysis of DNA methylation in single cells
Agostina Bianchi, Michael Scherer, Roser Zaurin, Kimberly Quililan, Lars Velten & Renée Beekman
Additional file 1. Supplementary Figures S1-S17.
Additional file 1 of scTAM-seq enables targeted high-confidence analysis of DNA methylation in single cells
Agostina Bianchi, Michael Scherer, Roser Zaurin, Kimberly Quililan, Lars Velten & Renée Beekman
Additional file 1. Supplementary Figures S1-S17.
Additional file 2 of Accrual of organ damage in Behçet’s syndrome: trajectory, associated factors, and impact on patients’ quality of life over a 2-year prospective follow-up study
Alberto Floris, Matteo Piga, Riccardo Laconi, Gerard Espinosa, Giuseppe Lopalco, Luisa Serpa Pinto, Nikolaos Kougkas, Jurgen Sota, Andrea Lo Monaco, Marcello Govoni, Luca Cantarini, George Bertsias, João Correia, Florenzo Iannone, Ricard Cervera, Carlos Vasconcelos, Alessandro Mathieu & Alberto Cauli
Additional file 2: Supplementary Table 1. Baseline features of the extension BODI cohort recruited for the analysis of the association between damage accrual and Heath related quality of life (n=147).
Additional file 1 of Safety, efficacy, and pharmacokinetics of gremubamab (MEDI3902), an anti-Pseudomonas aeruginosa bispecific human monoclonal antibody, in P. aeruginosa-colonised, mechanically ventilated intensive care unit patients: a randomised controlled trial
Jean Chastre, Bruno François, Marc Bourgeois, Apostolos Komnos, Ricard Ferrer, Galia Rahav, Nicolas De Schryver, Alain Lepape, Iftihar Koksal, Charles-Edouard Luyt, Miguel Sánchez-García, Antoni Torres, Philippe Eggimann, Despoina Koulenti, Thomas L. Holland, Omar Ali, Kathryn Shoemaker, Pin Ren, Julien Sauser, Alexey Ruzin, David E. Tabor, Ahmad Akhgar, Yuling Wu, Yu Jiang, Antonio DiGiandomenico … & Hasan S. Jafri
Additional file 1: Supplementary Methods, Results, Tables and Figures.
Autophagy-mediated NCOR1 degradation is required for brown fat maturation and thermogenesis
Alba Sabaté-Pérez, Montserrat Romero, Paula Sànchez-Fernàndez-de-Landa, Stefania Carobbio, Michail Mouratidis, David Sala, Pablo Engel, Paula Martínez-Cristóbal, Josep A Villena, Sam Virtue, Antonio Vidal-Puig, Manuel Palacín, Xavier Testar & Antonio Zorzano
Brown adipose tissue (BAT) thermogenesis affects energy balance, and thereby it has the potential to induce weight loss and to prevent obesity. Here, we document a macroautophagic/autophagic-dependent mechanism of peroxisome proliferator-activated receptor gamma (PPARG) activity regulation that induces brown adipose differentiation and thermogenesis and that is mediated by TP53INP2. Disruption of TP53INP2-dependent autophagy reduced brown adipogenesis in cultured cells. In vivo specific-tp53inp2 ablation in brown precursor cells or in adult mice decreased the expression of...
Autophagy-mediated NCOR1 degradation is required for brown fat maturation and thermogenesis
Alba Sabaté-Pérez, Montserrat Romero, Paula Sànchez-Fernàndez-de-Landa, Stefania Carobbio, Michail Mouratidis, David Sala, Pablo Engel, Paula Martínez-Cristóbal, Josep A Villena, Sam Virtue, Antonio Vidal-Puig, Manuel Palacín, Xavier Testar & Antonio Zorzano
Brown adipose tissue (BAT) thermogenesis affects energy balance, and thereby it has the potential to induce weight loss and to prevent obesity. Here, we document a macroautophagic/autophagic-dependent mechanism of peroxisome proliferator-activated receptor gamma (PPARG) activity regulation that induces brown adipose differentiation and thermogenesis and that is mediated by TP53INP2. Disruption of TP53INP2-dependent autophagy reduced brown adipogenesis in cultured cells. In vivo specific-tp53inp2 ablation in brown precursor cells or in adult mice decreased the expression of...
Affiliations
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August Pi i Sunyer Biomedical Research Institute17
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University of Barcelona5
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University of Cagliari4
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University of Crete4
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University of Queensland4
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Saarland University4
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Max Planck Institute for Informatics4
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University of Siena3
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University of Bari Aldo Moro3
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North West Agriculture and Forestry University2