Urosepsis is a life-threatening condition that needs to be addressed without delay. Two critical issues in its management are: (1) Appropriate empirical antibiotic therapy, considering the patients general condition, comorbidity, and the pathogen expected; and (2) Timing of imaging to identify obstruction requiring decompression. To identify risk factors associated with 30-day mortality in patients with urosepsis. From a cohort of 1,605 community-onset bloodstream infections (CO-BSI), 282 patients with urosepsis were identified in a Swedish county...

Supplementary Material 1

Additional file 3. Guidelines for data charting

Additional file 1. Interview schedule.

Additional file 1: Fig. S1. Flow cytometry estimation of the genome size for A. rhodopa female and male. Fig. S2. TE subclass landscapes of two species. Fig. S3. Repeat profiles of the remaining 31 shared TEs between two species. Fig. S4. Low-level piRNA silencing in A.rhodopa ovary. Fig. S5. Correlation analysis of K2P distance of TE with TE abundance and piRNA abundance.

Supplemental material, sj-doc-1-acr-10.1177_02841851221140668 for PET/MR versus PET/CT for locoregional staging of oropharyngeal squamous cell cancer by Lennart Flygare, Secil Telli Erdogan and Karin Söderkvist in Acta Radiologica

Multi-omics datasets represent distinct aspects of the central dogma of molecular biology. Such high-dimensional molecular profiles pose challenges to data interpretation and hypothesis generation. ActivePathways is an integrative method that discovers significantly enriched pathways across multiple datasets using statistical data fusion, rationalizes contributing evidence and highlights associated genes. As part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2658 cancers across 38 tumor types, we integrated...

Supplemental material, sj-docx-1-tpp-10.1177_20451253231151514 for Incidence of hyperthyroidism in patients with bipolar or schizoaffective disorder with or without lithium: 21-year follow-up from the LiSIE retrospective cohort study by Ingrid Lieber, Michael Ott, Robert Lundqvist, Mats Eliasson and Ursula Werneke in Therapeutic Advances in Psychopharmacology

Additional file 1: Table s3. Test of normally distributed differences between R1 and F. Legend R1 relative regional cerebral blood flow measured with [18F]FE-PE2I, F relative regional cerebral blood flow measured with [15O]H2O PET.

Supplemental material, sj-pdf-1-ijb-10.1177_13670069221139155 for A longitudinal study of episodic memory recall in multilinguals by Mariana Vega-Mendoza, Daniel Eriksson Sörman, Maria Josefsson and Jessica K. Ljungberg in International Journal of Bilingualism

Supplemental Material for Infiltrating immune cells in prostate cancer tissue after androgen deprivation and radiotherapy by Ann Erlandsson, Marie Lundholm, Johan Watz, Anders Bergh, Elitsa Petrova, Farhood Alamdari, Thomas Helleday, Sabina Davidsson, Ove Andren and Firas Tarish in International Journal of Immunopathology and Pharmacology.

The aim of this study was to investigate if there are differences in symptom ratings and plasma concentrations of oxylipins as a measure of acute inflammation between individuals with building-related symptoms (BRS) and referents during exposure to rooms where people experienced BRS and rooms where they did not experience BRS. Medically examined individuals with BRS and healthy, age and sex matched referents working in the same building were exposed for 60 min. Ratings of symptoms...

Objectives. The use of implantable cardioverter defibrillators (ICDs) in long QT syndrome (LQTS) patients is essential in high-risk patients. However, it is sometimes used in patients without high-risk profiles for whom the expected benefit may be lower than the risk of ICD harm. Here, we evaluated ICD benefit and harm by assessing risk according to risk scores and pre-ICD clinical characteristics. Design. We studied 109 Swedish LQTS patients drawn from the Swedish ICD and Pacemaker...

Urosepsis is a life-threatening condition that needs to be addressed without delay. Two critical issues in its management are: (1) Appropriate empirical antibiotic therapy, considering the patients general condition, comorbidity, and the pathogen expected; and (2) Timing of imaging to identify obstruction requiring decompression. To identify risk factors associated with 30-day mortality in patients with urosepsis. From a cohort of 1,605 community-onset bloodstream infections (CO-BSI), 282 patients with urosepsis were identified in a Swedish county...

Additional file 1: Supplementary file 1. Supplemental: Databases search strategies.

Additional file 1: Supplementary Table 1. Gender comparison of the mean values of the distribution and total scores of the different stromal biomarkers (Col1, Col4, a-SMA and MMP-9) regarding the different tumour groups (N0T and N1T). No significant differences were found between males and females regarding the expression of stromal biomarkers.

Additional file 4: Table s1. Difference in rCBFR measured as F (H2O) and R1 (FE-PE2I) between patients and healthy controls (T-test results). Legend Measures are averaged left and right hemisphere rCBFR values. rCBFR: relative regional cerebral blood flow. HC Healthy controls; rCBFR relative regional cerebral blood flow. F relative regional cerebral blood flow measured with [15O]H2O PET. R1 relative regional cerebral blood flow measured with [18F]FE-PE2I.

Additional file 1. Supplementary material regarding (i) the definition of cancer cases for HCC, GBC, Adv.PrC and Loc.PrC; (ii) the definition and implementation of the data-shared lasso; (iii) the models used to derive point estimates and confidence intervals from the model selected by the data-shared lasso; and (iv) the univariate analysis conducted for comparison.

Supplemental material, sj-doc-1-acr-10.1177_02841851221140668 for PET/MR versus PET/CT for locoregional staging of oropharyngeal squamous cell cancer by Lennart Flygare, Secil Telli Erdogan and Karin Söderkvist in Acta Radiologica

Cancers require telomere maintenance mechanisms for unlimited replicative potential. They achieve this through TERT activation or alternative telomere lengthening associated with ATRX or DAXX loss. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, we dissect whole-genome sequencing data of over 2500 matched tumor-control samples from 36 different tumor types aggregated within the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium to characterize the genomic footprints of these mechanisms. While the...

Supplemental material, sj-docx-1-sph-10.1177_19417381221147305 for A Longitudinal Case-Control Study of a Female Athlete Preinjury and After ACL Reconstruction: Hop Performance, Knee Muscle Strength, and Knee Landing Mechanics by Josefine E. Naili, Jonas L. Markström and Charlotte K. Häger in Sports Health: A Multidisciplinary Approach

Stress-related exhaustion is associated with cognitive deficits, measured subjectively using questionnaires targeting everyday slips and failures or more objectively as performance on cognitive tests. Yet, only weak associations between subjective and objective cognitive measures in this group has been presented, theorized to reflect recruitment of compensational resources during cognitive testing. This explorative study investigated how subjectively reported symptoms of cognitive functioning and burnout levels relate to performance as well as neural activation during a response...

Microspore transfers the developmental fate into embryogenesis in vitro regulated by determinant factors of stress-induced. However, the key regulators of microspore embryogenesis (ME) are still largely undiscovered to reveal the mechanism of cell fate transition. Here, we report that Phospholipase C (PLC) is involved at the early stages of ME in Nicotiana tabacum. NtPLC2/3/4 are expressed at the initial stages of ME. The expression levels of NtPLC2/3 are transient activated after 3 days in culture,...

The aim of this study was to investigate if there are differences in symptom ratings and plasma concentrations of oxylipins as a measure of acute inflammation between individuals with building-related symptoms (BRS) and referents during exposure to rooms where people experienced BRS and rooms where they did not experience BRS. Medically examined individuals with BRS and healthy, age and sex matched referents working in the same building were exposed for 60 min. Ratings of symptoms...

Objectives. The use of implantable cardioverter defibrillators (ICDs) in long QT syndrome (LQTS) patients is essential in high-risk patients. However, it is sometimes used in patients without high-risk profiles for whom the expected benefit may be lower than the risk of ICD harm. Here, we evaluated ICD benefit and harm by assessing risk according to risk scores and pre-ICD clinical characteristics. Design. We studied 109 Swedish LQTS patients drawn from the Swedish ICD and Pacemaker...