194 Works

The association of fatty liver and risk of hepatocellular carcinoma in HBV or HCV infected individuals: a systematic review and meta-analysis

Cheng-Long Han, Bao-Wen Tian, Chun-Cheng Yang, Ya-Fei Yang, Yun-Long Ma, Zi-Niu Ding, Lun-Jie Yan, Hui Liu, Zhao-Ru Dong, Zhi-Qiang Chen, Jian-Guo Hong, Dong-Xu Wang & Tao Li
Fatty liver (FL) is reportedly a risk factor for hepatocellular carcinoma (HCC) in individuals affected with Hepatitis C (HCV) or B (HBV) virus. However, the results are contradictory, necessitating a meta-analysis. Sixteen relevant studies involving 88,618 individuals were retrieved from the Cochrane Library, PubMed, MEDLINE, Embase, and Scopus databases from their inception to 10 December 2022. The hazard ratios (HR) and 95% confidence intervals (CI) were analyzed. Liver biopsy-proven FL may be a significant risk...

The association of fatty liver and risk of hepatocellular carcinoma in HBV or HCV infected individuals: a systematic review and meta-analysis

Cheng-Long Han, Bao-Wen Tian, Chun-Cheng Yang, Ya-Fei Yang, Yun-Long Ma, Zi-Niu Ding, Lun-Jie Yan, Hui Liu, Zhao-Ru Dong, Zhi-Qiang Chen, Jian-Guo Hong, Dong-Xu Wang & Tao Li
Fatty liver (FL) is reportedly a risk factor for hepatocellular carcinoma (HCC) in individuals affected with Hepatitis C (HCV) or B (HBV) virus. However, the results are contradictory, necessitating a meta-analysis. Sixteen relevant studies involving 88,618 individuals were retrieved from the Cochrane Library, PubMed, MEDLINE, Embase, and Scopus databases from their inception to 10 December 2022. The hazard ratios (HR) and 95% confidence intervals (CI) were analyzed. Liver biopsy-proven FL may be a significant risk...

Influence of organic dispersant on nuclear grade anion exchange resin and their interaction behavior

Yu Wang, Tianping Wang, Xuxiang Jia & Chunsong Ye
Polyacrylic acid (PAA) was used as an organic dispersant in the secondary circuit of nuclear power plants, which could interact with anion exchange resin and affect its properties in the condensate polishing treatment system. This study investigated the kinetics, isotherms, and thermodynamics characteristics of PAA adsorption on anion exchange resin. The results suggested that the inhibition of PAA adsorption on resin can be achieved by lowering the PAA concentration and temperature. In addition, the adsorption...

Red and processed meat intakes and cardiovascular disease and type 2 diabetes mellitus: An umbrella systematic review and assessment of causal relations using Bradford Hill’s criteria

Erica R. Hill, Lauren E. O’Connor, Yu Wang, Caroline M. Clark, Bethany S. McGowan, Michele R. Forman & Wayne W. Campbell
Observational research suggests higher red and processed meat intakes predict greater risks of developing or dying from cardiovascular diseases (CVD) and type 2 diabetes mellitus (T2DM), but this research limits causal inference. This systematic review of reviews utilizes both observational and experimental research findings to infer causality of these relations. Reviews from four databases were screened by two researchers. Reviews included unprocessed red meat (URM), processed meat (PM), or mixed URM + PM intake, and...

Additional file 2 of Deficiency of exchange protein directly activated by cAMP (EPAC)-1 in mice augments glucose intolerance, inflammation, and gut dysbiosis associated with Western diet

Preeti Dinesh Virwani, Lin Cai, Patrick Ka Kit Yeung, Gordon Qian, Yingxian Chen, Lei Zhou, Jason Wing Hon Wong, Yu Wang, Joshua Wing Kei Ho, Kui Kai Lau, Pei-Yuan Qian & Sookja Kim Chung
Additional file 2. R scripts used for bioinformatics analysis.

Intraperitoneal administration of thermosensitive hydrogel Co-loaded with norcantharidin nanoparticles and oxaliplatin inhibits malignant ascites of hepatocellular carcinoma

Susu Xiao, Yu Wang, Wenqiong Ma, Ping Zhou, Biqiong Wang, Zhouxue Wu, Qian Wen, Kang Xiong, Yanlin Liu & Shaozhi Fu
Malignant ascites is a common complication of some advanced cancers. Although intraperitoneal (IP) administration of chemotherapy drugs is routinely used to treat cancerous ascites, conventional drugs have poor retention and therefore need to be administered frequently to maintain a sustained anti-tumor effect. In this study, a thermosensitive hydrogel composite loaded with norethindrone nanoparticles (NPs) and oxaliplatin (N/O/Hydrogel) was developed to inhibit ascites of hepatocellular carcinoma (HCC) through IP injection. N/O/Hydrogel induced apoptosis in the H22...

Intraperitoneal administration of thermosensitive hydrogel Co-loaded with norcantharidin nanoparticles and oxaliplatin inhibits malignant ascites of hepatocellular carcinoma

Susu Xiao, Yu Wang, Wenqiong Ma, Ping Zhou, Biqiong Wang, Zhouxue Wu, Qian Wen, Kang Xiong, Yanlin Liu & Shaozhi Fu
Malignant ascites is a common complication of some advanced cancers. Although intraperitoneal (IP) administration of chemotherapy drugs is routinely used to treat cancerous ascites, conventional drugs have poor retention and therefore need to be administered frequently to maintain a sustained anti-tumor effect. In this study, a thermosensitive hydrogel composite loaded with norethindrone nanoparticles (NPs) and oxaliplatin (N/O/Hydrogel) was developed to inhibit ascites of hepatocellular carcinoma (HCC) through IP injection. N/O/Hydrogel induced apoptosis in the H22...

Influences of arbuscular mycorrhizal fungi on crop growth and potentially toxic element accumulation in contaminated soils: A meta-analysis

Li Chen, Fayuan Wang, Zhiqin Zhang, Herong Chao, Haoran He, Weifang Hu, Yi Zeng, Chengjiao Duan, Ji Liu & Linchuan Fang
Soil pollution from potentially toxic elements (PTEs) is a serious environmental issue worldwide that affects agricultural safety and human health. Arbuscular mycorrhizal fungi (AMF), as ecosystem engineers, can alleviate PTE toxicity in crop plants. However, the comprehensive effects of AMF on crop performance in PTE-contaminated soils have not yet been recognized globally. Here, a meta-analysis of 153 studies with 3213 individual observations was conducted to evaluate the effects of AMF on the growth and PTE...

Additional file 2 of Preliminary validation of the pica, ARFID and rumination disorder interview ARFID questionnaire (PARDI-AR-Q)

Rachel Bryant-Waugh, Casey M. Stern, Melissa J. Dreier, Nadia Micali, Lucy J. Cooke, Megan C. Kuhnle, Helen Burton Murray, Shirley B. Wang, Lauren Breithaupt, Kendra R. Becker, Madhusmita Misra, Elizabeth A. Lawson, Kamryn T. Eddy & Jennifer J. Thomas
Additional file 2. PARDI-AR-Q Self 14+.

Additional file 6 of Repetitive mild TBI causes pTau aggregation in nigra without altering preexisting fibril induced Parkinson’s-like pathology burden

Vedad Delic, Joshua H. Karp, Maynard Guzman, Gabriel R. Arismendi, Katherine J. Stalnaker, Julia A. Burton, Kathleen E. Murray, Joshua P. Stamos, Kevin D. Beck, Arpine Sokratian, Andrew B. West & Bruce A. Citron
Additional file 6. Figure 6S. TH+ neurons, pTau inclusions and αSyn inclusion were counted using image J. TH staining was used identify SNpc and draw region of interest (ROI). αSyn and pTau aggregates localized to TH+ cell bodies were manually counted and normalized to the area of the ROI. TH+ dopaminergic neurons containing αSyn pathology A. TH + neurons in SNpc containing pTau pathology B. TH+ SNpc neurons of sham control rats containing no aggregates...

COVID-19 vaccination in people living with HIV and AIDS (PLWHA) in China: A cross-sectional study

Xuan Lv, Chaobo Zhao, Bing Song, Huihuang Huang, Su Song, Hai Long, Weidong Liu, Min Du, Min Liu & Jue Liu
COVID-19 appears to put people living with HIV and AIDS (PLWHA) at a higher risk of catastrophic consequences and mortality. However, investigations on the hesitancy and vaccination behavior of PLWHA in China were lacking compared to the general population. From January 2022 to March 2022, we conducted a multi-center cross-sectional survey of PLWHA in China. Logistic regression models were used to examine factors associated to vaccine hesitancy and COVID-19 vaccine uptake. Among 1424 participants, 108...

Additional file 3 of Metabolic profiling and pharmacokinetic studies of Baihu-Guizhi decoction in rats by UFLC-Q-TOF–MS/MS and UHPLC-Q-TRAP-MS/MS

Yan He, Zhenkun Zhou, Weijie Li, Yanqiong Zhang, Ruoyao Shi, Tao Li, Linlin Jin, Hongliang Yao, Na Lin & Hao Wu
Additional file 3: Figure S3. The chromatogram of selectivity of the analytes in rat serum.

Red and processed meat intakes and cardiovascular disease and type 2 diabetes mellitus: An umbrella systematic review and assessment of causal relations using Bradford Hill’s criteria

Erica R. Hill, Lauren E. O’Connor, Yu Wang, Caroline M. Clark, Bethany S. McGowan, Michele R. Forman & Wayne W. Campbell
Observational research suggests higher red and processed meat intakes predict greater risks of developing or dying from cardiovascular diseases (CVD) and type 2 diabetes mellitus (T2DM), but this research limits causal inference. This systematic review of reviews utilizes both observational and experimental research findings to infer causality of these relations. Reviews from four databases were screened by two researchers. Reviews included unprocessed red meat (URM), processed meat (PM), or mixed URM + PM intake, and...

Additional file 3 of Scaffold-mediated switching of lymphoma metabolism in culture

Rachana Bhatt, Dashnamoorthy Ravi, Andrew M. Evens & Biju Parekkadan
Additional file 3: Figure S3. 13C isotope tracer labeling to elucidate metabolic flux variations between 2D and 3D grown DLBCL cell lines. (A) C13 labeled total pool (B) C13 fractional labelling.

sj-docx-1-aut-10.1177_13623613221138687 – Supplemental material for Categorical perception of Mandarin lexical tones in language-delayed autistic children

Yicheng Rong, Yi Weng, Fei Chen & Gang Peng
Supplemental material, sj-docx-1-aut-10.1177_13623613221138687 for Categorical perception of Mandarin lexical tones in language-delayed autistic children by Yicheng Rong, Yi Weng, Fei Chen and Gang Peng in Autism

Corticosteroid prevents COVID-19 progression within its therapeutic window: a multicentre, proof-of-concept, observational study

Yang Li, Xian Zhou, Tao Li, Shiji Chan, Yiqi Yu, Jing-Wen Ai, Haocheng Zhang, Feng Sun, Qiran Zhang, Lei Zhu, Lingyun Shao, Bin Xu & Wenhong Zhang
Critically ill patients with coronavirus diseases 2019 (COVID-19) are of grave concern. Those patients usually underwent a stage of excessive inflammation before developing acute respiratory distress syndrome. In this study, we test the hypothesis that short-term, low-to-moderate-dose corticosteroids would benefit patients when used in the early phase of excessive inflammation, namely, the therapeutic window. Among a Shanghai cohort and a validation cohort, we enrolled COVID-19 patients showing marked radiographic progression. Short-term, low-to-moderate-dose corticosteroids were considered...

Antioxidant, antibacterial, and anti-SARS-CoV Activity of Commercial Products of Xylopia (Xylopia aethiopica)

Claudia Melo, Rosemary Perdomo, Fadel Yerima, Oneil Mahoney, Nadjet Cornejal, Sahar Alsaidi, Shepherd Coron, Thierry Bonnaire, Shimin Zhang, Thomas M. Zydowsky, Christine Priano , Jose A. Fernandez Romero, H. Rodolfo Juliani & Adolfina Koroch

Assessment of Seed Quality of Selected African Leafy Vegetables Produced in Western Kenya using informal and semi-formal seed systems

Christine Ndinya, Fekadu Dinssa, James E. Simon, Naman Nyabinda, Norah Maiyo, Stephen Weller, Martins Odendo, Eunice Onyango, Michael Mwangi & Noel Makete

Improving Income and Nutrition of Smallholder Farmers in Eastern Africa using a Market-First Science-Driven Approach to Enhance Value Chain Production of African Indigenous Vegetables

James E. Simon, Stephen Weller, Daniel Hoffman, Ramu Govindasamy, Xenia Morin, Emily V. Merchant, Fekadu F. Dinssa, Emil Van Wyk, David Byrnes, Martins Odendo, Christine Ndinya, Henry H.A. Mvungi, Justus Ochieng, Norah Maiyo, Mebelo Mataa, John Shindano, Himoonga Bernard Moonga, J. Steve Yaninek, Qingli Wu, Naman Nyabinda & Victor Afari-Sefa

Novel mutation in TSPAN12 associated with familial exudative vitreoretinopathy in a Chinese pedigree

Zhen Song, Mo Li, Chang Wang, Yu Wang, Lihua Zhang, Na Li, Ruifang Yang & Ping Sun
Familial exudative vitreoretinopathy (FEVR) is a rare retinal disorder characterised by incomplete retinal vascular development. Symptoms vary widely from none to blindness even within the same family. Multiple genes related to the Wnt pathway have been found to be associated with FEVR. Recent studies identified tetraspanin 12 (TSPAN12) as a cause of the autosomal dominant inheritance form of FEVR. Here, we describe a novel TSPAN12 mutation in a Chinese family with FEVR. Targeted next-generation sequencing...

Optimization, reconstruction and heterologous expression of the gene cluster encoding toluene/o-xylene monooxygenase from Pseudomonas stutzeri in Escherichia coli and its successive hydroxylation of toluene and benzene

Bo Wang, Feng Gao, Jing Xu, Jianjie Gao, Zhenjun Li, Lijuan Wang, Fujian Zhang, Yu Wang, Yongsheng Tian, Rihe Peng & Quanhong Yao
Biological treatment is a cost-effective and environmentally friendly technique for treating toluene. However, this process is limited by the type and quantity of toluene degraders that can be applied to different environments and methods. It is a feasible solution to constructing new genetic engineering organisms for toluene degradation through biotechnology. To facilitate genetic manipulation and improve gene expression, the toluene/o-xylene monooxygenase locus from Pseudomonas stutzeri was reconstructed and artificially synthesized. All six genes were optimized...

Optimization, reconstruction and heterologous expression of the gene cluster encoding toluene/o-xylene monooxygenase from Pseudomonas stutzeri in Escherichia coli and its successive hydroxylation of toluene and benzene

Bo Wang, Feng Gao, Jing Xu, Jianjie Gao, Zhenjun Li, Lijuan Wang, Fujian Zhang, Yu Wang, Yongsheng Tian, Rihe Peng & Quanhong Yao
Biological treatment is a cost-effective and environmentally friendly technique for treating toluene. However, this process is limited by the type and quantity of toluene degraders that can be applied to different environments and methods. It is a feasible solution to constructing new genetic engineering organisms for toluene degradation through biotechnology. To facilitate genetic manipulation and improve gene expression, the toluene/o-xylene monooxygenase locus from Pseudomonas stutzeri was reconstructed and artificially synthesized. All six genes were optimized...

Classification and expression analysis of cucumber (Cucumis sativus L.) callose synthase (CalS) family genes and localization of CsCalS4, a protein involved in pollen development

Hongyun Wang, Shoujun Cao, Tao Li, Lili Zhang, Jiangang Yao, Xiubo Xia & Ruiqing Zhang
Callose plays an important role in plant development and response to multiple biotic and abiotic stresses. Callose synthase (CalS; EC 2.4.1.34), the main enzyme in callose synthesis, has been studied in a number of crops but not in cucumber (Cucumis sativus L.). In this study, 10 genes encoding putative callose synthase were identified and classified into four clades. Expression levels of the 10 CsCalS genes, which varied considerably, were detected in most analyzed organs. Transcription...

Additional file 2 of Activation of arcuate nucleus glucagon-like peptide-1 receptor-expressing neurons suppresses food intake

Ishnoor Singh, Le Wang, Baijuan Xia, Ji Liu, Azeddine Tahiri, Abdelfattah El Ouaamari, Michael B. Wheeler & Zhiping P. Pang
Additional file 2: Figure S2. GLP-1 receptor neuron distribution in the whole brain. Representative images of GLP-1R-ires-cre mouse crossed with Ai14 tdTomato reporter mice line.

Registration Year

  • 2023
    21
  • 2022
    126
  • 2021
    22
  • 2020
    25

Resource Types

  • Text
    194

Affiliations

  • Rutgers, The State University of New Jersey
    194
  • West China Hospital of Sichuan University
    109
  • Zhejiang University
    107
  • Shanghai Jiao Tong University
    105
  • Fudan University
    87
  • Chinese Center For Disease Control and Prevention
    86
  • Southern Medical University
    85
  • Central South University
    81
  • Capital Medical University
    79
  • University of Science and Technology of China
    79