148,234 Works

Gene expression analysis in primary lung cancers.

Marie-Pierre Puissegur, Pascal Barbry, Kevin Lebrigand, Véronique Hofman, Paul Hofman & Bernard Mari
Gene expression was analysed in 13 pairs of primary lung cancers and their corresponding non cancerous lung tissues. The specimens were obtained from the Nice Hospital Tumor Bio Bank, France. Dye swap-experiment were designed by comparing cancerous tissue versus adjacent normal lung tissue.This experiment has been deposited in the Gene Expression Omnibus (GEO) database under reference number GSE18694.

Liquefied Wood as an Adhesive for Particleboard Production

N. Čuk, S. Medved & M. Kunaver
Wood can be liquefied and used as a feedstock for production of different polymer materials, such as polyesters, polyurethanes and adhesives. The aim of our research was to evaluate the utilization of liquefied wood as an adhesive in a single-layer and a three-layer particleboard production. We also determined gel times for the mixtures of liquefied wood and melamine-formaldehyde or melamine-urea-formaldehyde resin. Results showed that gel time increased with liquefied wood loading and decreased with temperature...

Comparison of mouse dendritic cell subsets by genome-wide expression profiling

Marc Dalod, Robbins Scott, Doulaye Dembele, Philippe Kastner & Susan Chan
Spleen or lymph node resident DCs are subdivided into conventional DC (cDC) subsets (CD11b and CD8alpha in mouse; BDCA1 and BDCA3 in man) and plasmacytoid DCs (pDCs). It is currently unclear if these various DC populations belong to a unique hematopoietic lineage and if the subsets identified in the mouse and human systems are evolutionary homologs. To bring novel insights into these questions, we sought conserved genetic signatures for these DCs through the analysis of...

Contrast-enhanced breast MRI: association between malignancy and feeding vessels

Nicola Verardi
Purpose Methods and Materials Results Conclusion References Personal Information

Natural killer cells and innate immunity

Eric Vivier
Natural Killer (NK) cells are lymphocytes of the innate immune system that recognize and induce the lysis of a variety of target cells, including virally-infected cells, tumor cells, and allogenic cells without prior specific sensitization. In addition, NK cells elaborate a variety of regulatory cytokines including IFNg, TGFß1, TNFa, IL-1bß, IL-10, G-CSF, and GM-CSF and CC-chemokines, such as RANTES, MIP-1a and MIP-1bß which are involved in the elimination of intracellular pathogens in vivo, as well...

Response of Caenorhabditis elegans to infection by Drechmeria coniospora at 24 hours post exposure

Jonathan Ewbank
Transcription profiling of Caenorhabditis elegans after an exposure of 4 hours to the fungal pathogen Drechmeria coniospora, and a post exposure of 24 hours. This experiment has been deposited in the Array Express database under reference number E-MEXP-768.

Rheology of colloidal systems

Editors@Appliedrheology.Org, Editor Applied Rheology & Martin Kroger
Peer-reviewed journal article

Spatial localisation of metabolites in the Charentais melon fruit

Benoit Biais, J William Allwood, Catherine Deborde, Yun Xu, Mickael Maucourt, Bertrand Beauvoit, Warwick B Dunn, Daniel Jacob, Royston Goodacre, Dominique Rolin & Annick Moing
Spatial localisation of metabolites was investigated on one representative fruit for each cultivar by direct 1H-NMR profiling of juice or GC-EI-TOF-MS profiling of tissue extracts collected from different locations in the fruit flesh. This experiment has been deposited in the MeRy-B database, a plant metabolomics platform allowing the storage and visualisation of Nuclear Magnetic Resonance (NMR) metabolic profiles from plants (http://www.cbib.u-bordeaux2.fr/MERYB/).

Study of the Reaction Front Thickness in a Biomass Fixed-Bed Combustor

D. Patiño, D. Copena, J.C. Moran & E. Granada
The aim of this work is to analyze the behaviour of the reaction front thickness in a biomass combustor depending on the air mass flow rate. With this purpose, some modifications are introduced in a real fixed-bed combustor to continuously measure the depth of the bed’s surface. This new device coupled with the thermocouples used to measure the pass of the different fronts will allow us to record the thickness’ evolution of the drying, devolatilisation...

Analysis of sulfated oligosaccharrides by Mass Spectrometry

Florence Gonnet, Régis Daniel & Jeanine Tortajada
The structural heterogeneity of fucoidan with respect to linkage and sulfate position is still a limitation to trace clear correlations between the structure and biological activities of this polysaccharide, although much effort has been made during the past years to elucidate its structure complexes( DNA and polypeptides or polyamines). Recent studies have demonstrated the usefulness of tandem mass spectrometry for the sequencing of glycosaminoglycan oligosaccharides and the differentiation of sulfated isomers. Indeed, the fragmentation of...

Einsiedeln, Stiftsbibliothek, Codex 302(450) : Wandelbertus, Boethius, Ausonius, Gregorius, Arator, Prosper, Prudentius, Aldhelmus, Bonifatius

Aurelius Prudentius Clemens, Heinrich Von Ligerz, Diaconus Arator, Papa Gregorius I, Ferrariensis Lupus, Schireburnensis Aldhelmus, Sanctus Bonifatius, Anicius Manlius Severinus Boethius, Decimus Magnus Ausonius, Prumiensis Wandalbertus, Gallus Morel & De Aquitania Prosper
A composite manuscript composed of two volumes of collected works, written during the 9th and 10th centuries in eastern France or southwest Germany. It includes works by Wandelbertus, Boethius, Ausonius, Gregory, Arator, Prosper, Prudentius, Aldhelmus and Boniface.

Effect of sulfated oligosaccharides (heparin and fucoidan) on the oligomerization of stromal cell-derived factor-1

Soraya Fermas, Florence Gonnet, Angela Sutton, Nathalie Charnaux, Barbara Mulloy, Yuguo Du, Françoise Baleux & Régis Daniel
We investigate the dimerization of SDF-1 in microM concentration and in the presence of sulfated oligosaccharides, using affinity capillary electrophoresis (ACE) hyphenated to electrospray ionization-mass spectrometry (ESI/MS). Chemokine stromal cell-derived factor-1 (SDF-1) is a potent chemoattractant involved in leukocyte trafficking and metastasis. Heparan sulfate on the cell surface binds SDF-1 and may modulate its function as a coreceptor of this chemokine. A major effect of the glycosaminoglycan binding may be on the quaternary structure of...

Breast ultrasonography in young Asian women: Analyses of BI-RADS final assessment category according to the symptoms

Yu-Mee Sohn
Purpose Methods and Materials Results Conclusion References Personal Information

Suz12 ChIP-on-chip of mouse embryonic stem cell

Pierre Cauchy, Touati Benoukraf, Romain Fenouil, Frédéric Koch, Jean-Christophe Andrau & Pierre Ferrier
We aim to identify target sequences of suz12, a member of the polycomb group proteins (PcG) PRC2 (polycomb repressive complex 2). We study the role played by this polycomb complex on genetic plasticity during embryonic development in undifferentiated mouse embryonic stem cells (day 8). Suz12 is required for trimethylation of the tail of histone H3 on lysine 27 (H3K27me3). This epigenetic modification of chromatin induces dynamic repression of many target genes involved in developmental pathways....

Long bones manifestations of congenital syphilis

Thiago de Souza
Learning objectives Background Imaging findings OR Procedure details Conclusion Personal Information References

MR and CT anatomy and the pathology of skull base focusing on pterygopalatine fossa

Susumu Kandatsu
Learning objectives Background Imaging findings OR Procedure details Conclusion Personal Information References

Dendritic cells and antiviral defenses

Marc Dalod
The goal of our research is to identify new molecular pathways regulating the biology of DC subsets or more generally innate immune responses to viral infection. The model used is murine cytomegalovirus (MCMV) infection. The specific aims are 1) to determine the molecular bases regulating in vivo differentiation and anti-viral functions of DC subsets, 2) to investigate further NK cell anti-viral and immunoregulatory functions during viral infection, and 3) to identify viral molecules and cellular...

Ein helvetisches Brandgrab von der Engehalbinsel in Bern

Hansjürgen Müller-Beck & Elisabeth Ettlinger

Mapping the Quantitative Carrier Lifetime and Doping Concentration with Micro Resolution

F.D. Heinz, P. Gundel, M.C. Schubert & W. Warta
25th European Photovoltaic Solar Energy Conference and Exhibition / 5th World Conference on Photovoltaic Energy Conversion, 6-10 September 2010, Valencia, Spain; 498-503

Response of Caenorhabditis elegans to infection by Drechmeria coniospora at 12 hours post exposure

Jonathan Ewbank
Transcription profiling of Caenorhabditis elegans after an exposure of 4 hours to the fungal pathogen Drechmeria coniospora, and a post exposure of 12 hours. This experiment has been deposited in the Array Express database under reference number E-MEXP-767.

Analysis of Synthetic Polymers by LC-MS using an APCI Interface

Bernard Desmazières, Wiliam Buchmann, Peran Terrier & Jeanine Tortajada
In this work, the performance of the APCI interface will be investigated in SEC and LC-MS coupling applied to the analysis of industrial polymers up to molecular masses of 5 kDa: polyethers; polysiloxanes, and copolymers of siloxanes. Representative applications will be described to highlight benefits and limitations of the APCI technique.

Zürich, Zentralbibliothek, Ms. D 155 : Latin homilies on New Testament texts, preached by a monk from St. Gall

(:Unav)
Latin homilies by a St. St. Gall monk, delivered in various churches in the territory of the Fürstabtei (Bishop's Abbey) of St. Gall between 1674 and 1691.

Differential roles of ROR gamma-t in the development of NKp46+ spleen (LTIL) cells and NKp46+ NK cells in gut and skin

Damien Chaussabel, Elena Tomasello, Eric Vivier, Carmelo Luci, Ana Reynders & Ivaylo Ivanov
Natural killer (NK) cells are NKp46+CD3- lymphocytes that can perform granule-dependent cytotoxicity and produce interferon-gamma, when isolated from blood, lymphoid organs, lung, liver and uterus. Here we identify in dermis, gut lamina propria and cryptopatches, very distinct populations of NKp46+CD3- cells with reduced ability to degranulate and to produce interferon-gamma. In gut, the transcription factor RORgamma-t and CD127 (IL-7R alpha) defined a novel subset of NKp46+CD3- that is reminiscent of lymphoid tissue inducer (LTi)-like cells....

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