8,946 Works

Cannabis utilisé à des fins non-médicales: Feu vert pour des essais pilotes ciblés?

Valérie Junod
La présente contribution présente le projet fédéral soumis à la consultation et visant à autoriser les cantons qui le souhaitent à mener des essais contrôlés de consommation récréative de cannabis. Elle en expose les limites, proposant notamment de laisser aux chercheurs la responsabilité de définir le cercle des consommateurs autorisés à participer à de tels essais. Le projet dans son ensemble est à saluer, en ce qu'il facilitera le débat scientifique, social, politique, débat d'autant...

In-depth peer review by anonymous panels of experts with predefined expertise criteria through an online platform.

Stephanie Boue
This protocol describes the conduct of in-depth peer review of study reports, data, and additional material by panels of experts, which are recruited and managed on an online platform by a third party, independent from the sponsor of the review.

Measurement of corticosterone in rodent fecal samples (PMI)

Ee Tsin Wong & Blaine Phillips
This protocol describes the quantification of corticosterone in feces using an enzyme linked immunoassay kit (Corticostrone EIA kit, Cayman Chemicals, USA). The assay is based on the competition between corticosterone contained in a sample and a corticosterone-acetylcholine esterase (AChE) conjugate for a limited amount of corticosterone antiserum. An AChE substrate is then added to the plate to obtain a colorimetric reaction proportional to the binding, and inversely proportional to the amount of corticosterone present in...

Krisenmomente in der ›Guckkastenbühne‹

Hanna Voss
Ein Gespräch mit Benny Claessens zu Hello Useless – For W and Friends

Lipidomics Analysis (rodents, Zora, PMI)

Terhi Vihervaara, Kim Ekroos, Stephanie Boue & Bjorn Titz
Lipidomics analysis of tissues from an in vivo inhalation study.

Aerosol uptake and exposure in whole body exposure studies (PMI)

Blaine Phillips
This protocol describes the characterization of aerosols as well as biomarkers of exposure (COHb, markers of exposure in urine, nicotine metabolites in plasma and in urine) relevant to whole body exposure studies with rodents.

Analysis of indoor air constituents: carbon monoxide (CO), nitrogen monoxide (NO) and nitrogen oxides (NOx) (PMI)

Maya Mitova, Catherine Goujon-Ginglinger & Camille Cluse
The protocol describes required steps to operate two sensors for online quantification of respectively carbon monoxide (CO), Nitrogen monoxide (NO) and Nitrogen oxides (NOx) that are gas markers in Environmental Tobacco Smoke (ETS).

Eye tracking in virtual reality

Viviane Clay, Peter König & Sabine U. König
The intent of this paper is to provide an introduction into the bourgeoning field of eye tracking in Virtual Reality (VR). VR itself is an emerging technology on the consumer market, which will create many new opportunities in research. It offers a lab environment with high immersion and close alignment with reality. An experiment which is using VR takes place in a highly controlled environment and allows for a more in-depth amount of information to...

Indirekte Nutzung von Computerprogrammen

Gianni Fröhlich-Bleuler
Braucht der Anwender eine Lizenz, wenn er über ein Drittsystem auf ein Computer­programm zugreift und er es indirekt nutzt? In komplexer werdenden IT-Systemlandschaften wird dieser Gebrauch der Software immer wichtiger. Der folgende Beitrag beleuchtet die indirekte Nutzung von Programmen aus urheberrechtlicher Sicht.

Lung volume measurement in rodent studies (PMI)

Blaine Phillips
The protocol describes how to estimate lung volume via the fluid displacement or using the Cavalieri principle.

Microsaccades reflect the dynamics of misdirected attention in magic

Anthony S. Barnhart, Francisco M. Costela, Susana Martinez-Conde, Stephen L. Macknik & Stephen D. Goldinger
The methods of magicians provide powerful tools for enhancing the ecological validity of laboratory studies of attention. The current research borrows a technique from magic to explore the relationship between microsaccades and covert attention under near-natural viewing conditions. We monitored participants’ eye movements as they viewed a magic trick where a coin placed beneath a napkin vanishes and reappears beneath another napkin. Many participants fail to see the coin move from one location to the...

Atherosclerotic plaque size measurement with Micro-CT imaging (rodents) (PMI)

Blaine Phillips
This protocol describes the procedure to measure the area of atherosclerotic plaques covering the aortic arch or other blood vessels of interest using micro-CT imaging.

Indirekter Gegenentwurf zur Konzernverantwortungs­initiative - Haftungsnorm im Einklang mit der schweizerischen Tradition

Franz Werro
Die Konzernverantwortungsinitiative wie der Gegenentwurf bauen mit der Geschäftsherrenhaftung auf einer allgegenwärtigen und in ihrer schweizerischen Ausgestaltung im internationalen Vergleich zurückhaltenden Haftungsnorm auf. Die Übertragung dieser Haftung auf Konzernverhältnisse folgt sodann einem klaren in- wie ausländischen Trend. Beide Vorlagen erweitern hingegen den geltenden Haftungsrahmen auch im vorliegend menschenrechtlichen Zusammenhang nicht, sondern konkretisieren ihn lediglich. Die im Gegenentwurf verankerte Haftungsregelung fällt zudem auffallend einschränkend aus. Zu nennen ist neben dem Entscheid für den unternehmerischen Entlastungsbeweis auch...

»Outside of Your Day-to-Day Comfort Zone«

Anne Bonfert & Hanna Voss
An Interview with Ant Hampton on The Thing – An Automatic Workshop in Everyday Disruption

Enabling workers to prevention: Description of Quebec occupational therapists' practices aiming to establish the antecedents of preventive behaviours at work

Pierre-Yves Therriault & Alexandra Lecours
Introduction. Occupational therapists have a unique expertise in enabling workers to adopt prevention behaviours. However, their practices in this area have not been studied yet. Aim. The aim of this study was to describe Quebec occupational therapists’ practices related to the antecedents of preventive behaviours at work. Method. According to a mixed descriptive research design, semi-structured interviews were conducted with 13 occupational therapists working in occupational health. Interviews were designed to document the importance, frequency,...

«Rote Plakette» für Deutschlands Luftreinhaltung

Britta Uhlmann & Lena Hehemann
In mehreren europäischen Mitgliedstaaten werden die Sickstoffdioxid-Grenzwerte der Luftreinhalterichtlinie seit Jahren überschritten und somit Unionsrecht verletzt. Die EU-Kommission hat im Mai 2018 den letzten Schritt des Vertragsverletzungsverfahrens eingeleitet und Klage gegen die Bundesrepublik Deutschland erhoben. Der EuGH wird nun die deutschen Luftreinhaltmassnahmen auf den Prüfstand stellen – es bleibt abzuwarten, ob der EuGH Deutschland für seine Versäumnisse die «rote Karte» zeigen wird. In der Zwischenzeit widmet sich der vorliegende Beitrag der Frage, wie sich das...

Julie Paradis

Sylvie Tétreault
Sans résumé.

Are left- and right-eye pupil sizes always equal?

Gonca Gokce Menekse Dalveren & Nergiz Ercil Cagiltay
Eye movements provide very critical information about the cognitive load and behaviors of human beings. Earlier studies report that under normal conditions, the left- and right-eye pupil sizes are equal. For this reason, most studies undertaking eye-movement analysis are conducted by only considering the pupil size of a single eye or taking the average size of both eye pupils. This study attempts to offer a better understanding concerning whether there are any differences between the...

Theaterpublikum – das unbekannte Wesen. Annäherungen an eine vernachlässigte Figur

Doris Kolesch
L’enquête artistique sur le rôle et la fonction du public n’a pas commencé avec l’Art de la Performance dans les années 1960. Tout le 20e siècle a été marqué par l’expérimentation, la transformation et le questionnement de ce qu’est un public et de ce qu’il devrait faire ou ne pas faire. Alors que Bertolt Brecht demandait un nouvel »art de regarder« et qu’Antonin Artaud exigeait de plonger les spectateurs dans un »bain d’électricité psychique où...

Identification of a Loss-of-Function Mutation in the Context of Glutaminase Deficiency and Neonatal Epileptic Encephalopathy

Hubertus C M T Prinsen, Roderick H J Houwen, Maarten Lequin, Peter M Van Hasselt, Ralph Fingerhut, Michele Losa, Johannes R Lemke, Oliver Maier, Birgit Schiebergen-Bronkhorst, Bernhard Schmitt, Benjamin Büttner, Lynne Rumping, Judith J M Jans, Nanda M Verhoeven-Duif, Rami Jamra, Jan-Ulrich Schlump, Fried J T Zwartkruis & Holger Rehmann

Freie Republik HORA – Regie und Schauspiel als fortwährender Aushandlungsprozess

Sarah Marinucci & Marie Urban
Ein Gespräch mit Gianni Blumer (Schauspieler Theater HORA) und Nele Jahnke (Stv. künstlerische Leiterin Theater HORA)

Who trusts the news media? Exploring the factors shaping trust in the news media in German-speaking Switzerland

Dorothee Arlt
Although a decline of trust in the news media can be observed in many countries, in international comparison, Switzerland is still considered one of the countries with a relatively high level of media trust. Nevertheless, knowledge concerning the factors that promote and hinder media trust in Switzerland is still limited. Building on the research on media trust and media scepticism, this study investigates the effects of political orientation, political disenchantment, populist attitudes, and news exposure...

A Step Forward in Cancer Informatics—It Is Mandatory to Make Guidelines Machine Readable

Ivan Igrutinovic, Paul-Henry Mackeprang, Eugenia Vlaskou Badra, Alexandros Tsikkinis & Nikola Cihoric
Clinical guidelines are general recommendations for practicing clinicians regarding prevention, diagnosis and treatment of a given disease. One of the most comprehensive and used guidelines are developed and regularly updated by the National Comprehensive Cancer Network (NCCN). Guidelines are readily available for download in portable document format (PDF). A machine-readable representation of NCCN guidelines is currently not available. In this writing, we argue on the necessity that clinical guidelines should be published in a machine-readable...

La construcción del espacio turístico a través de la fraseología metafórica

Gianluca Pontrandolfo & Sara Piccioni
This article explores the metaphorical strategies conveyed by phraseological units in a subsection of the Linguaturismo corpus (Calvi 2011). Through a quali-quantative analysis, metaphorical phraseological units related to space were identified and classified, with a view to identifying the persuasive strategies necessary to create the image of the tourist destination in the reader/traveler's mind.The analysis followed a three-step methodology: a) semi-automatic elaboration of a list of potentially metaphorical N-grams; b) identification of phraseological patterns in...

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